Ionotropic glutamate receptor that features to be a cation permeable ligand-gated ion channel, gated by L-glutamate as well as the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at numerous synapses from the central anxious method. Binding from the excitatory neurotransmitter L-glutamate induces a conformation